Synthetic Pages - an Interactive Database of Chemical Procedures

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SyntheticPages is a freely available interactive database of synthetic chemistry. We publish practical and reliable organic, organometallic and inorganic chemical synthesis, reactions and procedures deposited by synthetic chemists. Synthetic methods on the site are updated continuously by chemists working in academic and industrial research laboratories.

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We are delighted to announce that the Septemeber 2015 CEM/SyntheticPages Prize for the best SyntheticPage has been awarded to:

Dr Richard Williams (rcnet chemicals) for his page on synthetic cannabinoids and the reduction of nitro-groups.

Richard will receive a cheque for £500, thanks to the generous sponsorship of SyntheticPages from CEM

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Recent Pages

  • Full information on 1-(thiophen-2-yl)-2-methylaminopropane - Methioproamine (18th Sept 2015)
  • A last resort method for methyl ester hydrolysis using trimethyltin hydroxide under microwave conditions. (Andrew McCarroll)
  • Nitrile reduction using Pd/C (Tim Snape)
  • Iron-mediated reduction of aromatic nitro- groups to amines. (Andrew McCarroll)
  • Palladium catalysed cross-coupling of acyl electrophiles and vinyl nucleophiles (Andrew Evitt)
  • Highly regioselective hydroformylation of methyl crotonate (Geoffrey Roff)

Selected reaction:

Reaction Scheme

Reaction of an amide enolate with an alkyl halide; Substituted Pyrrolidinones by Stephen Caddick

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