Synthetic Pages - an Interactive Database of Chemical Procedures

“IPEDS” are  Image and Performance Enhancing Drug and SARMS are Selective Androgen Receptor Modulators.

Andranine developed in the 1990s was found to have a remarkable effect on muscle growth. Bodybuilders were switching from anabolic steroids to Andranine as they thought there were less side effects. Professor JT Dalton went into partnership with a pharmaceutical company to develop a class of medicines called “ SARMS”  Selective Androgen Receptor Modulators. Andranine was the first and then Ostarine. Both of these failed to get regulatory approval  for the legal supply chain. However these products have been used by many people in the athletic community.

means any drug or other substance that is a selective androgen receptor agonist chemically unrelated to testosterone, estrogens, progestins, corticosteroids, and dehydroepiandrosterone; and

“(ii) includes—

“(I) (S)-N-(4-cyano-3-(tri­fluor­o­meth­yl)phen­yl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide (commonly known as ‘ostarine’ or ‘enobosarm’);

“(II) 4-((R)-2-((R)-2,2,2-trifluoro-1-hydroxyethyl)pyrrolidin-1-yl)-2-(tri­fluor­o­meth­yl)benzonitrile (commonly known as ‘LGD-4033’ or ‘ligandrol’);

“(III) 9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3,6-dihydro-7H-pyrrolo[3,2-f]quin­olin-7-one (commonly known as ‘LGD-3303’);

“(IV) isopropyl (S)-(7-cyano-4-(pyridin-2-ylmethyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-2 -yl)carbamate (commonly known as ‘LY2452473’ or ‘TT701’);

“(V) 2-chloro-4-(((1R,2S)-1-(5-(4-cy­an­o­phen­yl)-1,3,4-oxadiazol-2-yl)-2-hy­droxy­pro­pyl)amino)-3-methylbenzonitrile (commonly known as ‘RAD-140’);

“(VI) (S)-3-(4-acetamidophenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-(tri­fluor­o­meth­yl)­phen­yl)propanamide (commonly known as ‘andarine’);

“(VII) 2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxotetrahydro-1H-pyrrolo[1,2-c]imidazol- 2(3H)-yl)-3-methylbenzonitrile (com­monly known as ‘BMS-564929’);

“(VIII) 6-ethyl-4-(trifluoromethyl)-6,7,8,9-tetrahydropyrido[3,2-g]quinolin-2(1H)-one (commonly known as ‘LG-121071’);

“(IX) (S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy- 2-methylpropanamide (commonly known as ‘S-23’);

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